ORAC 6.0 – “Oxygen Radical Absorbance Capacity” TEST.
Brunswick Laboratories, founded in 1997 is an internationally recognized, independent, clinical and pre-clinical testing and research laboratory focusing on phytochemical testing, human cells-based bioassays, and clinical studies for functional foods, nutritional supplements, and pharmaceutical products. A pioneer in the research and services related to antioxidants, phytochemicals and oxidative stress reduction. Since their establishment, through independent research and development they have created several independent intellectual patents and industry-leading core technologies.
The ORAC test was developed to provide a method for quantifying the antioxidant capacity found in food sources. It currently serves as a valuable tool for ongoing research to define the role of antioxidants in various industries such as the food, nutrition, cosmetic, and pharmaceutical arenas. It is an in vitro test that was an important advancement in commercially available analysis of the Peroxyl free-radical’s trapping ability of foods and ingredients. It has become a de facto standard in the natural products industry. However, the original ORAC method was just a starting point for comprehensive antioxidant analysis. The fact that there are a variety of “free radicals” that operate in humans – the most important of which are the primary radicals, Hydroxyl, Peroxyl, Peroxynitrite, Singlet Oxygen, and Superoxide Anion.
Brunswick laboratory has reported that even though the Peroxyl is the major free radical in the body, it represents no more than 27% of the total antioxidant potential of selected fruits and vegetables. In addition, the original ORAC method favors certain antioxidant substances over others (e.g., anthocyanins over carotenoids) due to the use of a single free radical source Peroxyl Radical. Brunswick Laboratories developed the ORAC 6.0 as an analytical tool for estimating the antioxidant capacity of substances. ORAC 6.0 provides a measure of the total antioxidant power of a food or nutrition product against the six predominant reactive oxygen species found in the body. It is a comprehensive suite of assays based on a unified ORAC method that enables antioxidant testing against these six primary reactive oxygen species.
This test expands the ORAC platform to measure the antioxidant capacity against each of the previous five (ORAC 5.0 Test) primary reactive oxygen species mentioned above as well as…
Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification.
Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes (such as SOD and Glutathione). It can damage virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids.
Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. In the skin, Peroxynitrite contributes to the breakdown of vital proteins.
Singlet Oxygen is generated in the skin. Singlet oxygen is highly unstable and durable. Carotenoids are very effective at scavenging singlet oxygen.
Superoxide Anion is a precursor of all other reactive oxygen species and sometimes is referred to as “the mother of free radicals.” It contributes to lipid and DNA damage. Antioxidants that scavenge superoxide anion also help prevent the formation of radicals such as hydrogen peroxide and hydroxyl.
Hypochlorite (HOCl) which is another important free radical that is commonly found in the body as a by-product of the metabolism of other free radicals. Direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions.
ORAC 6.0 substantially improves broad-spectrum antioxidant analysis and gives evidence of the diverse antioxidant potential of natural-source products against radicals other than just Peroxyl. Brunswick laboratory research shows that the antioxidants found in a wide range of natural products are beneficial against these primary radicals, and that in many cases a preponderance of a product’s antioxidant capacity is described by performance against the six free radicals included to the ORAC 6.0 panel.
FEED YOUR JOINTS has been evaluated by Brunswick Laboratory in the United States with the ORAC 6.0 Test and reached an index of 33 556 μmole TE/gram.
Providing 218 114 μmol TE per serving of (6.5g). You can see the test certificate HERE.
FEED YOUR JOINTS provides Vitamin C which contributes to normal collagen formation for the normal function of bones and cartilage. Plus Vitamin C, E, Manganese and extracts of Olive Leaf, Turmeric and Grape Seed which all act as antioxidants to contribute to the protection of cells from oxidative stress.
Food Supplements should not be used as a substitute for a varied and balanced diet & healthy lifestyle.